SHIELD – Medication Safety Assistant

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  SHIELD - medication safety assistant that flags dangerous drug interactions, allergy conflicts, and kidney risks using FHIR patient data

Inspiration

In Zimbabwe and across Africa, medication errors are a silent crisis. Dangerous drug interactions – like ACE inhibitors combined with NSAIDs leading to acute kidney injury – are common but preventable. Overburdened health systems often lack clinical pharmacists. I built SHIELD to provide an AI safety net that works with existing electronic health records via FHIR, starting in low-resource settings and scaling globally.

What it does

SHIELD is an A2A-enabled medication safety agent. Given a patient's medications, allergies, and kidney function (eGFR), it flags:

• High-risk drug-drug interactions (e.g., ACE inhibitor + NSAID)
• Allergy conflicts
• Medications requiring dose adjustment for renal impairment

Every response ends with a required medical disclaimer.

How we built it

I used Prompt Opinion's BYO Agent builder with the SHARP FHIR Context Extension. The agent is configured with a structured clinical checklist, A2A availability enabled, and published to the Marketplace. No custom code – all configuration-driven.

Challenges we ran into

Initially, the test patient had no clinical data, so the agent correctly reported "no medications found." I added a synthetic document with medications and labs, and the agent successfully flagged the drug interaction. The SHARP FHIR extension setup required careful toggling, but the documentation helped.

Accomplishments that we're proud of

A fully functional, published healthcare AI agent that demonstrates clinical reasoning without writing a single line of code. It meets all hackathon requirements: A2A, FHIR context, Marketplace listing, and medical disclaimer.

What we learned

The "last mile" in healthcare AI is connecting models to real (synthetic) clinical data via standards like FHIR. Prompt Opinion's SHARP extension makes this seamless.

What's next for SHIELD – Medication Safety Assistant

Expand to full African rollout with local drug formularies, add support for pediatric dosing checks, integrate with openEHR and national health information exchanges, and deploy offline-capable versions for rural clinics with limited internet.

Built With

• deepseek
• fhir
• health
• nexus
• obsstudio
• prompt-opinion
• sharp-extension