The lack of isolation in front-lines of the fight against the COVID-19 put the medical personnel under the infection risk. There are many cases that medical staff infected with the COVID-19, even with protective pieces of equipment such as masks, face shields, and exclusive clothes. The ICUs are also highly dangerous areas, and access to these would burden the risk of infection to the doctors, residences, and other medical staff. Unfortunately, the therapeutic activity inside the hospitals is not automated, and so far, all these efforts are done by a human factor. A solution that automates the Hygiene of the indoor environment (such as hospitals, public places, public transportation, and so on) is missing, and there is a gap between the required Hygiene standard and current protocols of Hygiene for the indoor environment. An autonomous application that is intelligent in filling this gap would preserve the lives and also diminish the cost and time of the Hygiene operation.