Answering questions such as “Which genes are related to breast cancer?” usually requires retrieving relevant publications through the PubMed search engine, reading these publications, and creating gene lists. This process is not only time-consuming, but also prone to errors. GLAD4U (Gene List Automatically Derived For You) is a new, free web-based gene retrieval and prioritization tool, which takes advantage of the NCBI’s Entrez Programming Utilities (E-utilities). Upon the submission of a query, GLAD4U retrieves the corresponding publications with eSearch before using Pubmed ID-Entrez Gene ID mapping tables provided by the NCBI to create a list of genes. A statistics-based prioritization algorithm ranks those genes into a list that is output to the user, usually within less than a minute. The GLAD4U user interface accepts any valid queries for PubMed, and its output page displays the ranked gene list and information associated with each gene, chronologically-ordered supporting publications, along with a summary of the run and links for file exports and for further functional enrichment analyses.

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