๐Ÿงฌ DoHealth

Understand a cancer. See it in 3D. Help fight it.

When someone you love is diagnosed with cancer, you feel helpless. DoHealth turns that helplessness into understanding โ€” and a way to help.

๐Ÿ”— Live demo ยท ๐ŸŽค Pitch slides ยท ๐Ÿ† Built for the DigitalOcean Gradient AI Hackathon โ€” AI for Social Good


๐Ÿ’” The problem

Every day, families receive a diagnosis packed with terrifying words โ€” "KRAS G12C," "EGFR L858R" โ€” and no way to make sense of them. The tools that explain cancer at the molecular level (PyMOL, RCSB, AlphaFold) are built for experts who already know the protein, the mutation, and the drug.

Everyone else โ€” the parent, the partner, the friend โ€” is locked out of understanding the disease attacking someone they love. And they desperately want to help.

๐Ÿ’ก The solution

DoHealth makes molecular oncology understandable and participatory for anyone. Ask in plain English, get three things:

๐Ÿง  1. Understand

GLM-5.2 explains the cancer, the mutation, and how the treatment works โ€” in warm, jargon-free language a scared family member can actually follow.

๐Ÿ”ฌ 2. Explore

The real protein target and the drug that binds it, in interactive 3D with the mutation highlighted โ€” pulled live from RCSB PDB, AlphaFold, and PubChem.

๐Ÿค 3. Contribute

Fold a novel protein on a real GPU with ESMFold. From Folding@home to the Foldit game, ordinary people have advanced cancer research for years โ€” now anyone can take part.

โšก Powered by DigitalOcean Gradient

๐Ÿค– Gradient serverless inference (GLM-5.2) Turns plain language into the exact structural biology that drives the 3D scene
๐Ÿš€ App Platform Hosts the full-stack app with auto-deploy
๐ŸŽ›๏ธ GPU Droplets (RTX 6000 Ada, 48GB) Live ESMFold protein folding

๐Ÿ“Š Data sources

All free, public, and open โ€” no API keys except Gradient:

Source What we pull
๐Ÿงฌ RCSB PDB Experimental protein 3D structures (by PDB ID, e.g. 6OIM)
๐Ÿ”ฎ AlphaFold DB Predicted structures (by UniProt ID) โ€” fallback when no experimental structure exists
๐Ÿ’Š PubChem Small-molecule drug 3D structures (by name)
๐ŸŽ›๏ธ ESMFold (facebook/esmfold_v1) Folds novel sequences into new structures, on our GPU
โญ Curated hero set KRAS ยท EGFR ยท BRAF ยท BCR-ABL reference cases

โค๏ธ Honest by design

In-silico predictions are hypotheses for scientists to validate โ€” not treatments. DoHealth accelerates understanding and participation; it never diagnoses or prescribes. Handling a vulnerable audience responsibly isn't a limitation โ€” it's the point.


๐Ÿงฌ DoHealth โ€” because understanding is the first way to fight back.

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