With increased importance placed on personalized medicine and precision therapy in the biopharmaceutical industry, RNA-based therapeutics have become more relevant. Therefore, we want to use this method to further personalised medicine.

What it does

Our code creates transcription factor binding sites from binding motifs, and synthesizes ASOs to target top binding sites/sequences.

How we built it

Using JASPAR transcription factor motifs

Challenges we ran into

Creating a database of TFs and their motifs

Accomplishments that we're proud of

Incorporation of JASPAR motifs into R

What we learned

ASOs have not been shown to be used with DNA, therefore, this will be a new approach

What's next for ASO Targets

To create ASOs for all TFs to increase potential drug options

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