Alzheimer’s MRI Classification Using Deep Learning

Inspiration

Alzheimer’s disease affects memory, independence, and families. We wanted to explore how AI + MRI imaging could support research into early understanding of cognitive decline — not to replace doctors, but to learn how deep learning can recognize meaningful brain-scan patterns.

What We Built

We trained a ResNet-based deep learning model to classify MRI scans into four stages:

  • Non-Demented
  • Very Mild Demented
  • Mild Demented
  • Moderate Demented

We used transfer learning, a reproducible notebook, and a clean evaluation pipeline so others can easily follow and extend our work.

How We Built It

  1. Preprocessed MRI scans: resize → normalize → augment
  2. Fine-tuned a pretrained model on the dataset
  3. Evaluated using accuracy and weighted F1-score
  4. Integrated the trained model into a simple prediction app

Inline math example: ( \mathcal{L} = - \sum_i y_i \log(\hat{y}_i) )

Displayed math example:
$$ \text{Accuracy} = \frac{\text{Correct Predictions}}{\text{Total Samples}} $$

What We Learned

We learned a lot about:

  • Transfer learning techniques
  • Handling dataset imbalance
  • Evaluation metrics and debugging model collapse
  • The importance of reproducibility and transparency in healthcare AI

Results

Our final model achieved:

  • Accuracy: 92.89%
  • Weighted F1-score: 92.83%

These scores showed strong, consistent performance across all four classes.

Challenges

We encountered real-world issues such as:

  • Class-label inconsistencies
  • Environment differences
  • Early model collapse (fine-tuning pitfalls)
  • Maintaining full notebook reproducibility

Each challenge helped us strengthen the project and improve our workflows.

Example Code Block

puts "Hello World!"

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