3D Hemoglobin Structural Analysis

Inspiration

Understanding protein structure is fundamental in biology and medicine. This project was inspired by the need to combine computational analysis with interactive visualization to explore human hemoglobin's structural features.

What I Learned

• Analyzing chain lengths, RMSD between chains, and amino acid composition.
• Building interactive 3D molecular visualizations using py3Dmol.
• Integrating code, visualizations, and research report for professional presentation.

How I Built It

• Downloaded hemoglobin PDB file (1A3N) for structural data.
• Developed Python scripts to calculate chain lengths, RMSD, and amino acid composition.
• Generated an interactive 3D HTML model with py3Dmol.
• Created a professional research report and captured screenshots for visualization.

Challenges

• Handling different chain lengths and structural deviations in RMSD analysis.
• Making the 3D model interactive and visually clear for all users.
• Organizing the project files for GitHub, Figshare, Zenodo, and Devpost publication.

Links

• GitHub Repository: https://github.com/efe4r/hemoglobin_project
• Figshare DOI: https://doi.org/10.6084/m9.figshare.30257089
• Zenodo DOI: https://doi.org/10.5281/zenodo.17243278

Built With

• amino-acid-profiling
• github
• html
• libreoffice
• libreoffice-(report-export)
• pdb-data
• py3dmol
• python
• rmsd-comparisons