List of unsolved problems in biology
Show definitions of each problem
Show definitions of each problem
Highlighting the mouse over a problem shows the definition
A world map to view where all the research is being conducted
Colors associated to each unsolved problem illustrating how long research has been going on without a total solution
Clicking on a unsolved problem for example “perception” pops below milestones with theories to why it is not solved widget
Clicking on a unsolved problem fr example “perception” pops below a countdown whether that is a timer clock, doomsday clock, or ranking sys.
Unsolved problem for example “perception” pops below a list manually added of all researchers and clinicians working in that particular area
Clicking on a unsolved problem for example “perception” pops below a donation widget showing how much $ is raise http://charitynavigator.org
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Theme song https://www.youtube.com/watch?v=pCL1N-XgUxk
Inspiration: Ellery Newton wondered why there wasn’t a cure for Parkinson’s Disease. He wanted to know what was being done to find the cure. He quickly realized that there were many other people out there wondering about other uncured diseases and unsolved problems in biology. Health Now is aiming to pull the information together to give this community a place. The mission is, "Starting with incurable diseases, organize the world's unsolved biology problems to make them accessible & solvable."
Currently in the public library system, people looking for a health database find that most of the information is found “through government portals such as Medline Plus and for global disease information the CDC - all of that information is free of charge.” And, “Rates on subscriptions to these depends on many factors - some companies due licensing based on how many people are part of a library, the type of information, how hard it is to find the information (or if it is completely proprietary - which drives up the cost quite a bit). Our databases range from $500-3000+ depending on topic and competitive pricing with their competitors.”
However, this website offers a low ranged subscription and is different because:
A community of interest where both people with diseases and their support groups can quickly find a place to connect with others under similar circumstances
Is for people who are so inclined this will be a central repository whereby people will be connected with the proper places to donate their funds or they can donate and those people with philanthropic intentions
This third reason for visiting this one of a kind portal and my original inspiration for starting this site is to provide the first stopping off point for anyone who would like to learn more about any one of these curable and uncurable debilitating diseases
Did you know Wikipedia lists the unsolved problems in biology? Disease, consciousness, biological aging etc., Our web app is going to aggregate the problems.
Challenges: Styling the webpages may be the most difficult part if teams have minimal experience with CSS.
“Progress requires an entire scientific community across academia and industry, with hundreds of contributors supplying both breakthroughs and steady incremental advances.” Hype vs Hope article
Accomplishments: You will (perhaps learn) how to setup a basic database to store values, and how to create an app on Google AppEngine.
What are the requirements for Health Now:
- A website that shows lists from wikipedia and its definition:
We want the ability to add to and remove the items on the lists (it shouldn’t just be a static list on the page) (Since it is a lot to keep up with the research that is being done, we’d like for others to be able to upload the information. We would want the ability to check it before it is posted on the site.) Have the ability to review the items before they get posted live.
Make sure there is a page for the public and separate page designated for scientists to help them solve the problems (Here is a suggestion for how the public comments ttps://codepen.io/search/pens?q=Comments&limit=all&type=type-pens) An example for collecting the “what”, recent publications: Research Gate—researchgate.net (Here is a suggestion for how the scientists collaborate https://codepen.io/search/pens?q=Material%20Sharing&order=popularity&depth=everything&show_forks=false) Also review the layout of Mayo Clinic (https://mayoclinic.pure.elsevier.com), NIH (https://clinicaltrials.gov), and Charity Navigator (https://www.charitynavigator.org), https://www.biorxiv.org, Wikipedia scientific journals, http://mendeley.com MIT solve it (solve.mit.edu) Opportunity Atlas Census track Health United States Department of Human Resources CDC US health (website competitor) Euromonitor
We would like to show what research has been done on the disease (collect all researchers and clinicians in the world working on a particular problem.) For example, Parkinson’s:
- Pubmed search – get names from Pubmed using a Parkinson’s disease query
- Conference search – get names of scientists from Parkinson’s conferences (speakers, poster abstracts, etc.)
- Parkinson’s organizations – get names from the websites of organizations that support patients and/or
Create a world map of research being conducted that shows all the companies and people globally working in each particular area. (Here is a suggestion for where to get a map https://codepen.io/search/pens?q=Worldmap&limit=all&type=type-pens) (The suggestion for the algorithm to collective information rather than manually input the information is Python—Beautiful soup to web crawl)
Have a countdown clock widget under each of the unsolved problems (Here is a suggestion for where to get a countdown https://codepen.io/search/pens?q=Countdown&limit=all&type=type-pens) Tensorflow—define what the task is then apply networks that are trained to recognize clinical trials to update the countdown. (Reference Clinical Trials — https://clinicaltrials.gov/_
Here's a website to view if you are a visual learner, and want to view your code in images http://brackets.io
Aggregate all the podcasts, conferences, and videos, interviews, ted talks, on each biological problem
Add (algorithm) The RG Score is a metric that measures scientific reputation based on how all of your work is received by your peers.
Add part that offers data completeness on google scholar that research gate doesn't
-Research filter for type such as clinical trial, break throughs and things like that 1) A less intense countdown clock. One that instead of an actual cure date says "hopefully cured within xx years" 2) An admin tab so you or any other admin can edit the site directly on the webpage instead of altering the backend. 3) A script that scrapes different research sources and automically adds Doctor and reasearch data onto the sites and maps instantly. 4) Potentially research more maps and find a more user friendly interactive map.
Who will work on Health Now:
- Lead designer, who works side-by-side with UI and CSS developers
- Full stack developers
- UX specialists
- Data scientists and any other necessary functions
Health Now company values: 1) We'll be the preferred web app for aggregating, and solving biological problems 2) Team members will say Health Now was the best company they'd ever worked for 3) Our users will write us love letters
"Here in the United States we spend 50 times more money on treating diseases than we do on research and prevention..we need to change that ratio and put more effort to being able to solve these problems from the outset...the problems out there now are complicated. They're complicated problems and not necessarily going to be solved by one genius working in isolation. So we want to change that. We want to support collaboration. Support collaboration between people who have different skills. So between scientists and engineers all working together contributing their unique knowledge to solving complex problems. The better we can be at solving our knowledge with each other efficiently and effectively, the fast everything will move forward." credit: pulled quote from the Chan Zuckerberg Initiative website
“What Facebook and ResearchGate have in common are two challenges. First of all, the members of the networks have to be continually encouraged to actively participate, otherwise the networks’ appeal is diminished. But above all the networks must find ways to earn money with the help of their users – otherwise, and this is where Mr. Madisch is right, even the largest financing isn’t worth talking about.
The challenge is to make money from the data users have supplied - without antagonizing them. Like Facebook, ResearchGate must first of all take care of challenge number one. For a year now, scientists have not only been able to set up profiles and upload study articles – across the world, some 2.5 million new publications are produced every month – but also share the data from on-going research projects with the community.
So far, the scientists have created pages for more than half a million new projects. Among them is one from NASA, which is simulating living conditions on Mars in Hawaii and keeping the scientific world informed about it in real time. “The majority of all scientific experiments fail,” said Mr. Madisch, who holds an M.D. and a Ph.D. “But we learn nothing about that in the journals. So we keep making the same mistakes again and again.” Moreover, he adds, it is burdensome that scientific data is stored in so many different places. ResearchGate, he says, wants to fundamentally change the way research is done – and, with it, save researchers time and money. The interest is there – but now it has to be monetized.
Scientists are embracing ResearchGate – 1.7 million registered users visit the platform once a week or more. One out of every three of them has uploaded at least one on-going project.” credit: pulled from https://www.google.com/amp/s/global.handelsblatt.com/companies/the-science-of-making-money-716003/amp
What's next: http://gust.com/companies/health-now If this is of interest to you, please donate: https://www.gofundme.com/manage/call-to-action-project That way I can continue the progress that has already been made. I will use the funds to pay coders to make further features.
Business plan -
Cash flow assumptions/projections -
Resource: Use Tableau and rapidminer for datascience.
ibm map by citations
Revenue streams use a library subscription $1000
$99.99 migrate $11.10/month host $2.99/month backup $80 ssl/year (5 pack $150 a year) $8/month scanning tools Scanning tool for web with firewall $75/month or $900 year for 5 sites Just scanning $22/ $275 scan websites for malware Web security plan 3 month/security plan $900 for 5 $240 for 1 $1150 scanning tool or scanning tool firewall combination Migration $500 $13 for deluxe hosting $2.99/month for each site $270 for 5 + 1 $339.84 year (cant for monthly 3 months $89.20)
Paywall - account processing, verification Charging nonprofits on the site* Find niche then fill out that niche
“The scientists never make any money. They’re always deluded into thinking they live in a just universe. That will reward them for their work and their inventions. And this is probably the fundamental delusion that scientists suffer from in our society.”
“You’re the smartest physicist of the 20th century. You come up with special relativity, you come up with general relativity. You don’t get to be a billionaire, you don’t even get to be a millionaire. It just somehow doesn’t work that way.”
“Scientists are operating in this sort of the world where all of the innovation is effectively competed away and they can’t capture any of it directly.”
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